Antioxidant beta-carotene use safe during radiation treatment for prostate cancer

[ Back to EurekAlert! ] Public release date: 31-May-2012
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Contact: Nicole Napoli
nicolen@astro.org
703-839-7336
American Society for Radiation Oncology

Despite past safety concerns, the antioxidant supplement beta-carotene, is safe to use during radiation therapy treatments for prostate cancer and does not increase the risk of prostate cancer death or metastases, according to a study in the May issue of the International Journal of Radiation OncologyBiologyPhysics, the official scientific journal of the American Society for Radiation Oncology (ASTRO).

The use of vitamin supplements and antioxidants is common, but the safety of using antioxidant supplements during radiation treatments for prostate cancer is controversial. Radiation therapy relies on the pro-oxidant effects of DNA, which involves damaging tumor cells while leaving normal cells unharmed. However, some scientists have suggested that supplemental antioxidants may weaken the oxidizing effects of radiation and potentially lead to cancer recurrence.

In the largest study to date of its kind, researchers followed 383 prostate cancer patients who were randomized to receive beta-carotene or placebo to determine if antioxidants could potentially counteract the pro-oxidant effects of radiation therapy and increase a patient's risk of death or metastases. The primary endpoint was prostate cancer death or bone metastases.

Researchers found no significant differences in lethal outcomes among the patients who took the antioxidant beta-carotene versus those who did not.

"This study shows that antioxidant supplementation with beta-carotene during radiation therapy does not appear to detract from the benefit of radiation therapy." Danielle Margalit, MD, MPH, lead author of the study and a radiation oncologist at the Dana-Farber Cancer Institute in Boston, said. "It also suggests that patients may continue to eat a well-balanced diet that contains foods with natural sources of antioxidants at the recommended daily amount."

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ASTRO is the largest radiation oncology society in the world, with more than 10,000 members who specialize in treating patients with radiation therapies. As the leading organization in radiation oncology, biology and physics, the Society is dedicated to improving patient care through education, clinical practice, advancement of science and advocacy. For more information on radiation therapy, visit www.rtanswers.org. To learn more about ASTRO, visit www.astro.org.


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[ Back to EurekAlert! ] Public release date: 31-May-2012
[ | E-mail | Share Share ]

Contact: Nicole Napoli
nicolen@astro.org
703-839-7336
American Society for Radiation Oncology

Despite past safety concerns, the antioxidant supplement beta-carotene, is safe to use during radiation therapy treatments for prostate cancer and does not increase the risk of prostate cancer death or metastases, according to a study in the May issue of the International Journal of Radiation OncologyBiologyPhysics, the official scientific journal of the American Society for Radiation Oncology (ASTRO).

The use of vitamin supplements and antioxidants is common, but the safety of using antioxidant supplements during radiation treatments for prostate cancer is controversial. Radiation therapy relies on the pro-oxidant effects of DNA, which involves damaging tumor cells while leaving normal cells unharmed. However, some scientists have suggested that supplemental antioxidants may weaken the oxidizing effects of radiation and potentially lead to cancer recurrence.

In the largest study to date of its kind, researchers followed 383 prostate cancer patients who were randomized to receive beta-carotene or placebo to determine if antioxidants could potentially counteract the pro-oxidant effects of radiation therapy and increase a patient's risk of death or metastases. The primary endpoint was prostate cancer death or bone metastases.

Researchers found no significant differences in lethal outcomes among the patients who took the antioxidant beta-carotene versus those who did not.

"This study shows that antioxidant supplementation with beta-carotene during radiation therapy does not appear to detract from the benefit of radiation therapy." Danielle Margalit, MD, MPH, lead author of the study and a radiation oncologist at the Dana-Farber Cancer Institute in Boston, said. "It also suggests that patients may continue to eat a well-balanced diet that contains foods with natural sources of antioxidants at the recommended daily amount."

###

ASTRO is the largest radiation oncology society in the world, with more than 10,000 members who specialize in treating patients with radiation therapies. As the leading organization in radiation oncology, biology and physics, the Society is dedicated to improving patient care through education, clinical practice, advancement of science and advocacy. For more information on radiation therapy, visit www.rtanswers.org. To learn more about ASTRO, visit www.astro.org.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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Bee Gee?s Singer Robin Gibb Awakes From Coma

Bee Gee’s Singer Robin Gibb Awakes From Coma

Singer Robin Gibb has shocked his family after waking up from a coma after he became ill with pneumonia. Gibb’s spokesman, Doug Wright, says the [...]

Bee Gee’s Singer Robin Gibb Awakes From Coma Stupid Celebrities Gossip Stupid Celebrities Gossip News


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How Do I Earn Money These days By Web ?

No matter whether the particular economic system is great or bad I usually ask personally, how can I earn income these days? Whether or not you have a great job or even recently out of work, it is very important be considering ways that you can earn an extra income.

This can be to settle a few bills, or simply in order to appreciate an additional vacation this season with the family. Let?s quickly take a second and also discuss how we may earn money these days.

One way to make quick cash is to find something you sell that you already own. You can find excellent online language resources such as eBay and craigslist to put these things up for sale either in a set cost or via an market, that can allow you to earn money rapidly off of something you already personal.

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The great point regarding this really is you can do this while continuing the standard job. Therefore it is a great resource of additional income which is based off of your own routine. In addition, this enables you to create contacts along with other independent companies as well as authors. This means in case your work is lost you have a backup career previously prepared for.

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Learn more about earn money. Stop by Abhishek Thakur?s site where you can find out all about online moneysources.

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Microsoft retires Vista, Office 2007 from mainstream support this week

Microsoft will shift Windows Vista and Office 2007 into what it calls extended support over the next two days.

Vista, the problem-plagued operating system that never really took hold among users, will exit mainstream support on Tuesday, April 10. According to Microsoft, Office 2007 leaves mainstream support today.

In a product's extended support phrase, Microsoft continues to provide security patches to all users, but offers other fixes -- such as reliability and stability updates -- only to organizations that have signed support contracts with the company.

http://www.computerworld.com/s/article/9225979/Microsoft_retires_Vista_Office...

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Artifacts worth $3.2 million stolen from UK museum

(AP) ? Two Chinese artifacts with an estimated combined value of 2 million pounds ($3.2 million) have been stolen from a British museum, authorities said Saturday.

Two men and a woman from the West Midlands area have been arrested in connection with the Thursday night theft at Durham University's Oriental Museum, but the items had not yet been recovered, police said.

The northern England-based university confirmed that two "priceless" artifacts were stolen when thieves broke into a ground-floor gallery at the museum: a large jade bowl with a Chinese poem written inside that dates back to 1769, and a Dehua porcelain sculpture.

"We are extremely upset to have fallen victim to such a serious crime," museum curator Craig Barclay said in a statement. "The two pieces are highly significant in that they are fine examples of artifacts from the Qing Dynasty."

Police said they were still trying to locate "several outstanding suspects." The museum will be closed until further notice, the university said.

The university said police and security guards were alerted immediately by alarms, but declined to comment further on its security systems.

Associated Press

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fun games for kids to play at home . Education Board Games ? Fun ...

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